Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 15/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958265 | 0.93 | UTS2R (0.39) | UTS2RPPARAMDM2PPARGBCL2 | |
| SCHEMBL15163670 | 0.89 | UTS2R (0.38) | UTS2RPPARAMDM2PPARGBCL2 | |
| SCHEMBL15163671 | 0.89 | UTS2R (0.38) | UTS2RPPARAMDM2PPARGBCL2 | |
| SCHEMBL958625 | 0.89 | UTS2R (0.38) | UTS2RPPARAMDM2PPARGBCL2 | |
| SCHEMBL958964 | 0.82 | KMT2A (0.36) | — | |
| SCHEMBL116410 | 0.81 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL735527 | 0.81 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL3670614 | 0.79 | CYP2C19 (0.37) | — | |
| SCHEMBL956652 | 0.79 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL1869067 | 0.76 | UTS2R (0.46) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2183228-B1 | CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1 | VITAE PHARMACEUTICALS INC (US) | 2014-08-20 | — | — | EP | disclosed |