SCHEMBL1594945

SCHEMBL1594945

CCCCC=C(C)C(=O)OC(=O)C(C)=CC(C)C

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.34
FAAH O00519 2/20 0.33
EP300 Q09472 1/20 0.33
LMNA P02545 2/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
CTSK P43235 1/20 0.32
MAPT P10636 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
MAPK1 P28482 1/20 0.31
PRKCA P17252 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7709736 0.90 CYP2D6 (0.33) GRIK1CYP2D6CYP2C19
SCHEMBL7754867 0.88 EP300 (0.41) GRIK1FAAHEP300CYP2D6CYP2C19
SCHEMBL5459895 0.84 EP300 (0.47) FAAHEP300LMNACYP2C19MAPT
SCHEMBL5864613 0.83 GRIK1 (0.34) GRIK1FAAHEP300CYP2D6CYP2C19
SCHEMBL5461045 0.82 EP300 (0.37) GRIK1FAAHEP300CYP2D6CYP2C19
SCHEMBL15251310 0.82 EP300 (0.50) FAAHEP300LMNACYP2C19MAPT
SCHEMBL1001904 0.82 EP300 (0.37) GRIK1FAAHEP300CYP2D6CYP2C19
SCHEMBL4387815 0.82
SCHEMBL7087960 0.81 LMNA (0.43) GRIK1FAAHEP300LMNACYP2D6
SCHEMBL7613779 0.81 EP300 (0.36) GRIK1EP300CYP2D6CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9353286-B2 Powder compositions ALLNEX ITALY SRL (IT) 2016-05-31 US disclosed
EP-2247680-B1 POWDER COMPOSITIONS ALLNEX ITALY SRL (IT) 2015-04-01 EP disclosed
US-20140378611-A1 AQUEOUS URETHANE RESIN COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2014-12-25 US disclosed
US-7919544-B2 Ink-media set, ink composition, ink cartridge, inkjet recording method, inkjet recording apparatus, and ink recorded matter RICOH COMPANY, LTD. (JP) 2011-04-05 US disclosed
US-20100311896-A1 POWDER COMPOSITIONS CYTEC ITALY S.R.L. (IT) 2010-12-09 US disclosed
EP-2247680-A2 POWDER COMPOSITIONS Cytec Italy, S.R.L. (IT) 2010-11-10 EP disclosed
WO-2009095460-A2 POWDER COMPOSITIONS CYTEC ITALY S.R.L. (IT) 2009-08-06 WO disclosed
EP-2085440-A1 Powder Compositions Cytec Italy, S.R.L. (IT) 2009-08-05 EP disclosed
US-20090043028-A1 INK-MEDIA SET, INK COMPOSITION, INK CARTRIDGE, INKJET RECORDING METHOD, INKJET RECORDING APPARATUS, AND INK RECORDED MATTER RICOH COMPANY, LTD. (JP) 2009-02-12 US disclosed
EP-1927582-A1 Coatings for ceramic substrates CYTEC SURFACE SPECIALTIES, S.A. (BE) 2008-06-04 EP disclosed
US-4795783-A BLEND WITH HYDROXY VINYL POLYMER PPG INDUSTRIES, INC. (US) 1989-01-03 US disclosed