⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165390 | 0.81 | — | — | |
| SCHEMBL27452564 | 0.77 | — | — | |
| SCHEMBL159501 | 0.77 | — | — | |
| SCHEMBL4035315 | 0.77 | — | — | |
| SCHEMBL1827221 | 0.77 | MAPK1 (0.47) | — | |
| SCHEMBL4708946 | 0.77 | — | — | |
| Potassium Ion SCHEMBL29224327 | 0.76 | HCAR2 (0.41) | — | |
| SCHEMBL15556627 | 0.76 | — | — | |
| SCHEMBL20029123 | 0.76 | — | — | |
| SCHEMBL2629429 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040019046-A1 | Phenylacetamido-pyrazole derivatives and their use as antitumor agents | PHARMACIA ITALIA SPA (IT) | 2004-01-29 | — | — | US | claimed |
| US-9856210-B2 | Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis | KYOTO UNIVERSITY (JP) | 2018-01-02 | — | — | US | disclosed |
| US-20170217901-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | SOLVAY SA (BE) | 2017-08-03 | — | — | US | disclosed |
| EP-3174857-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | Solvay SA (BE) | 2017-06-07 | — | — | EP | disclosed |
| EP-2611437-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | UNIV KYOTO (JP) | 2017-03-29 | — | — | EP | disclosed |
| CN-102596913-B | Cannabinoid receptor modulators | 艾尼纳制药公司 | 2016-11-09 | — | — | CN | disclosed |
| WO-2016016298-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | SOLVAY SA (BE) | 2016-02-04 | — | — | WO | disclosed |
| EP-2980078-A1 | Process for the preparation of pyrazole-4-carboxamides | Solvay SA (BE) | 2016-02-03 | — | — | EP | disclosed |
| US-20130225642-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | KYOTO UNIVERSITY (JP) | 2013-08-29 | — | — | US | disclosed |
| EP-2611437-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029994-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | KYOTO UNIVERSITY (JP) | 2012-03-08 | — | — | WO | disclosed |
| US-20040019046-A1 | Phenylacetamido-pyrazole derivatives and their use as antitumor agents | PHARMACIA ITALIA SPA (IT) | 2004-01-29 | — | — | US | disclosed |
| EP-1345909-A1 | PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002048114-A1 | PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2002-06-20 | — | — | WO | disclosed |
| EP-0697623-B1 | Silver halide photographic material containing pyrazolone-pentamethine oxonol dye | FUJI PHOTO FILM CO LTD (JP) | 1998-03-25 | — | — | EP | disclosed |
| US-5633390-A | CONTROLLING LIGHT ABSORBED; CANBE BLEACHED OR DISSOVED IN PROCESSING SOLUTION; STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5563028-A | DYES HAVE SPECIFIC SPECTRAL ABSORPTION, CHEMICAL INACTIVITY IN PHOTOGRAPHIC REACTIONS, BLEACHABLE OR DISSOLUTION, PHOTOSTABILITY AND COLORFASTNESS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0697623-A1 | Silver halide photographic material containing pyrazolone-pentamethine oxonol dye | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-21 | — | — | EP | disclosed |