SCHEMBL159503

SCHEMBL159503

C=CCOC(C)OCC=C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 1/20 0.32
POLB P06746 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15384202 0.92 LMNA (0.35) LMNAMEN1KMT2A
SCHEMBL7592942 0.89
SCHEMBL5790760 0.88 MEN1 (0.32) LMNAMEN1KMT2ATDP1CA1
SCHEMBL5688482 0.86
SCHEMBL2831806 0.84
SCHEMBL441432 0.84
SCHEMBL10537932 0.82
SCHEMBL29281483 0.82 TSHR (0.36) LMNAMEN1KMT2APOLB
SCHEMBL466023 0.81
SCHEMBL483349 0.80 TDP1 (0.31) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9212118-B2 Synthesis of intermediates for preparing anacetrapib and derivatives thereof LEK PHARMACEUTICALS D.D. (SI) 2015-12-15 US claimed
US-8795787-B2 Surface modification GREINER BIO-ONE GMBH (DE) 2014-08-05 US claimed
US-20140135368-A1 SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF LEK PHARMACEUTICALS D.D. (SI) 2014-05-15 US claimed
EP-2655348-A1 SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF LEK Pharmaceuticals d.d. (SI) 2013-10-30 EP claimed
WO-2012085133-A1 SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF LEK PHARMACEUTICALS D.D. (SI) 2012-06-28 WO claimed
EP-2468736-A1 Synthesis of intermediates for preparing anacetrapib and derivates thereof LEK Pharmaceuticals d.d. (SI) 2012-06-27 EP claimed
EP-2252410-B1 SURFACE MODIFICATION GREINER BIO ONE GMBH (DE) 2011-12-14 EP claimed
US-20100234240-A1 SURFACE MODIFICATION GREINER BIO - ONE GMBH (DE) 2010-09-16 US claimed
US-6887824-B1 Divalent lanthanide reduction catalysts THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-05-03 US claimed
EP-1242468-A1 DIVALENT LANTHANIDE REDUCTION CATALYSTS The Regents of the University of California (US) 2002-09-25 EP claimed
WO-2001021667-A1 DIVALENT LANTHANIDE REDUCTION CATALYSTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-03-29 WO claimed
EP-0287956-B1 Process for the preparation of 5-formylevalerianic acid esters or the corresponding acetals BASF AG (DE) 1993-11-24 EP claimed
JP-2188544-A None JP disclosed
JP-3099034-A None JP disclosed
US-12529975-B2 Toner, developer, toner storage unit, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2026-01-20 US disclosed
US-20250316700-A1 ANODE COMPOSITION FOR LITHIUM-ION BATTERIES APB CORPORATION (JP) 2025-10-09 US disclosed
US-4346027-A UNSATURATED OXYGEN POLYMER AND A POLYOL MONSANTO COMPANY (US) 1982-08-24 US disclosed
US-4150237-A INTERMEDIATES IN THE FORMATION OF EPOXIDES THE DOW CHEMICAL COMPANY (US) 1979-04-17 US disclosed
US-4126746-A Halohydrin thioethers and method of preparation THE DOW CHEMICAL COMPANY (US) 1978-11-21 US disclosed
US-4071563-A Manufacture of pent-4-en-1-al BASF AKTIENGESELLSCHAFT (DT) 1978-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135368-A1 SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF CYP2B6, CYP4B1, CIAPIN1 LMNA 1641/4885MEN1 2799/4885KMT2A 2084/4885
US-12529975-B2 Toner, developer, toner storage unit, image forming apparatus, and image forming method ZFR, ZMYND8, SUN2 LMNA 4089/4885MEN1 4677/4885KMT2A 1570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.