Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12605756 | 0.92 | ESR1 (0.51) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL10446289 | 0.90 | ESR1 (0.41) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL15957763 | 0.86 | RAB9A (0.41) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL15957771 | 0.84 | RAB9A (0.45) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL15957768 | 0.82 | RAB9A (0.45) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL15957767 | 0.82 | RAB9A (0.45) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL15957761 | 0.82 | TRPV1 (0.39) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL15957758 | 0.81 | RAB9A (0.44) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL1664438 | 0.80 | RAB9A (0.43) | RAB9AESR1ESR2TRPV1SMN1; SMN2 | |
| SCHEMBL1663541 | 0.80 | RAB9A (0.43) | RAB9AESR1ESR2TRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809528-B2 | Quinazolinone derivatives useful as vanilloid antagonists | NOVARTIS AG (CH) | 2014-08-19 | — | — | US | disclosed |