Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.59 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | LTK | P29376 | 1/20 | 0.59 |
| ▸ | GRK5 | P34947 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
| ▸ | CDK7 | P50613 | 1/20 | 0.59 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.59 |
| ▸ | NEK4 | P51957 | 1/20 | 0.59 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.59 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595045 | 0.88 | ABCG2 (0.56) | MAPTKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL12669922 | 0.88 | KDM4E (0.55) | MAPTKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL8224937 | 0.84 | MAPT (0.55) | MAPTKDM4EALDH1A1ABCG2EGFR | |
| SCHEMBL2301864 | 0.84 | KDM4E (0.59) | MAPTKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL15958634 | 0.83 | MAPT (0.72) | MAPTKDM4EALDH1A1L3MBTL1ABCG2 | |
| SCHEMBL7691978 | 0.83 | ABCG2 (0.59) | MAPTKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL4016340 | 0.81 | ABCG2 (0.65) | MAPTKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL2302678 | 0.80 | MAPT (0.69) | MAPTKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL4018542 | 0.78 | ABCG2 (0.55) | MAPTKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL189161 | 0.77 | MEN1 (0.72) | MAPTKDM4EHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809264-B2 | Quinoxalinyl macrocyclic hepatitis C virus serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2014-08-19 | — | — | US | disclosed |