Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.59 |
| ▸ | KDR | P35968 | 2/20 | 0.59 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | LTK | P29376 | 1/20 | 0.59 |
| ▸ | GRK5 | P34947 | 1/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
| ▸ | CDK7 | P50613 | 1/20 | 0.59 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.59 |
| ▸ | NEK4 | P51957 | 1/20 | 0.59 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.59 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.59 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.59 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15958633 | 0.83 | MAPT (0.60) | ABCG2KDRDYRK3MAP4K4EGFR | |
| SCHEMBL2301864 | 0.82 | KDM4E (0.59) | ABCG2KDRDYRK3MAP4K4EGFR | |
| SCHEMBL2302678 | 0.81 | MAPT (0.69) | ABCG2KDRDYRK3MAP4K4EGFR | |
| SCHEMBL7696773 | 0.80 | NPSR1 (0.56) | ABCG2EGFRMEN1KMT2AHTT | |
| SCHEMBL7696554 | 0.79 | ABCG2 (0.58) | ABCG2EGFRMEN1KMT2ALMNA | |
| SCHEMBL4016340 | 0.79 | ABCG2 (0.65) | ABCG2KDRDYRK3MAP4K4EGFR | |
| SCHEMBL7695446 | 0.79 | ALDH1A1 (0.52) | ABCG2MAP4K4EGFRLTKMAPK8 | |
| SCHEMBL19129462 | 0.79 | ABCG2 (0.67) | ABCG2LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1085867 | 0.78 | MEN1 (0.71) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL20570001 | 0.78 | MAPT (0.54) | ABCG2KDRDYRK3MAP4K4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |