Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595031 | 0.85 | MEN1 (0.41) | KDM4EL3MBTL1LMNAALDH1A1TDP1 | |
| SCHEMBL12669839 | 0.85 | AKT1 (0.40) | KDM4EL3MBTL1LMNAALDH1A1TDP1 | |
| SCHEMBL7735370 | 0.81 | KDM4E (0.65) | KDM4EL3MBTL1LMNAALDH1A1TDP1 | |
| SCHEMBL453506 | 0.72 | KDM4E (0.48) | KDM4EL3MBTL1LMNAALDH1A1NPSR1 | |
| SCHEMBL30364989 | 0.72 | ALDH1A1 (0.53) | KDM4EL3MBTL1LMNAALDH1A1TDP1 | |
| SCHEMBL15958639 | 0.71 | KDM4E (0.51) | KDM4EL3MBTL1LMNAALDH1A1TDP1 | |
| SCHEMBL7640450 | 0.70 | NPC1 (0.43) | KDM4EL3MBTL1LMNAALDH1A1TDP1 | |
| SCHEMBL15958641 | 0.69 | KDM4E (0.45) | KDM4EL3MBTL1LMNAALDH1A1TDP1 | |
| SCHEMBL7474377 | 0.68 | NQO2 (0.56) | KDM4EL3MBTL1LMNAALDH1A1TDP1 | |
| SCHEMBL28116018 | 0.67 | TDP1 (0.50) | KDM4EL3MBTL1LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809264-B2 | Quinoxalinyl macrocyclic hepatitis C virus serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2014-08-19 | — | — | US | disclosed |