Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1891888 | 0.87 | CYP4F2 (0.42) | FFAR1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL38659422 | 0.87 | CYP4F2 (0.42) | FFAR1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL38660151 | 0.85 | KDM4E (0.46) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL1887566 | 0.85 | KDM4E (0.46) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL38661151 | 0.83 | CYP4F2 (0.41) | FFAR1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL1891542 | 0.83 | CYP4F2 (0.41) | FFAR1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL1810928 | 0.80 | KDM4E (0.45) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL17254705 | 0.79 | CYP4F2 (0.45) | FFAR1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL19209441 | 0.79 | MTNR1A (0.46) | FFAR1CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL1817206 | 0.79 | CCNC (0.39) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496544-B1 | GPBP INHIBITION USING Q2 PEPTIDOMIMETICS | FIBROSTATIN S L (SE) | 2014-08-20 | — | — | EP | disclosed |