Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | IAPP | P10997 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778109 | 0.90 | KDM4E (0.40) | TRPV1MCHR1KMT2AKDM4ECYP1A2 | |
| SCHEMBL3778110 | 0.90 | KDM4E (0.40) | TRPV1MCHR1KMT2AKDM4ECYP1A2 | |
| SCHEMBL3785173 | 0.86 | KDM4E (0.39) | TRPV1MCHR1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3785172 | 0.86 | KDM4E (0.39) | TRPV1MCHR1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3773270 | 0.81 | KDM4E (0.40) | TRPV1MCHR1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3773271 | 0.81 | KDM4E (0.40) | TRPV1MCHR1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL31031262 | 0.80 | TRPV1 (0.36) | TRPV1MCHR1KDM4E | |
| SCHEMBL13017801 | 0.77 | TRPV1 (0.52) | TRPV1LMNAMAPTKMT2AATM | |
| SCHEMBL3781790 | 0.76 | TRPV1 (0.42) | TRPV1LMNAKMT2AATMKDM4E | |
| SCHEMBL3781784 | 0.76 | TRPV1 (0.42) | TRPV1LMNAKMT2AATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054411-B1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORP (KR) | 2014-08-20 | — | — | EP | disclosed |