Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.36 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773270 | 0.88 | KDM4E (0.40) | TRPV1MCHR1GSK3AGSK3BACVR1 | |
| SCHEMBL3773271 | 0.88 | KDM4E (0.40) | TRPV1MCHR1GSK3AGSK3BACVR1 | |
| SCHEMBL3785172 | 0.81 | KDM4E (0.39) | TRPV1MCHR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL3785173 | 0.81 | KDM4E (0.39) | TRPV1MCHR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL3778109 | 0.80 | KDM4E (0.40) | TRPV1MCHR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL3778110 | 0.80 | KDM4E (0.40) | TRPV1MCHR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL15959233 | 0.80 | TRPV1 (0.38) | TRPV1MCHR1KDM4E | |
| SCHEMBL3772762 | 0.77 | KDM4E (0.40) | TRPV1MCHR1P2RX7KDM4ENPC1 | |
| SCHEMBL3772760 | 0.77 | KDM4E (0.40) | TRPV1MCHR1P2RX7KDM4ENPC1 | |
| SCHEMBL19660410 | 0.75 | TRPV1 (0.42) | TRPV1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12059412-B2 | Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethylpyridin-3-yl)-acrylamide and method for inhibiting crystal formation thereof | AMOREPACIFIC CORPORATION (KR) | 2024-08-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12059412-B2 | Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethylpyridin-3-yl)-acrylamide and method for inhibiting crystal formation thereof | SULT2A1, SULT1E1, SULT1A1 | TRPV1 2202/4885MCHR1 4202/4885MAP3K7 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.