SCHEMBL15959641

SCHEMBL15959641

CC(=O)c1c(C)c(C)c(C)n1C

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.38
USP2 O75604 1/20 0.36
GPR35 Q9HC97 1/20 0.35
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
HIF1A Q16665 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12374703 0.70 KDM4E (0.42) KMT2AKDM4EUSP2MEN1CYP1A2
SCHEMBL77684 0.67
SCHEMBL11277818 0.65 USP2 (0.44) KMT2AKDM4EUSP2GPR35MEN1
SCHEMBL24890410 0.63 KMT2A (0.33) KMT2AKDM4EMEN1MAPTMAPK1
SCHEMBL20519235 0.61 USP2 (0.49) KMT2AUSP2GPR35MEN1L3MBTL1
SCHEMBL22870151 0.61 KDM4E (0.47) KMT2AKDM4EUSP2MEN1MAPT
SCHEMBL16731958 0.60 USP2 (0.44) KMT2AKDM4EUSP2GPR35MEN1
SCHEMBL30932977 0.60 CYP3A4 (0.46) KMT2AKDM4EMEN1CYP1A2CYP3A4
SCHEMBL11893177 0.60 CYP3A4 (0.46) KMT2AKDM4EMEN1CYP1A2CYP3A4
SCHEMBL24890439 0.56 TSHR (0.32) KMT2ACYP1A2HPGDTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9228061-B2 Zirconium containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-01-05 US disclosed
US-20140235812-A1 Zirconium Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW CORNING CORPORATION (US) 2014-08-21 US disclosed