SCHEMBL15959693

SCHEMBL15959693

c1cc(-c2ccc3c(c2)c2ccccc2c2cc4c5cc6c7ccccc7c7cc(-c8cccc9c8sc8ccccc89)ccc7c6cc5n(-c5cccc6sc7ccccc7c56)c4cc32)cc(-c2cccc3c2sc2ccccc23)c1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
PRKDC P78527 3/20 0.41
PARP14 Q460N5 1/20 0.32
DNPH1 O43598 1/20 0.32
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
PIK3CD O00329 1/20 0.31
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31
LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15959774 1.00 ALOX5 (0.46) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL17248448 0.89 ALOX5 (0.48) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL15959675 0.86 ALOX5 (0.49) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL15959758 0.86 ALOX5 (0.49) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL15959692 0.86 ALOX5 (0.49) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL17248427 0.85 ALOX5 (0.51) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL26512506 0.85 ALOX5 (0.46) ALOX5PRKDCPARP14PIK3CDBRD4
SCHEMBL16133239 0.84 ALOX5 (0.62) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL16133229 0.84 ALOX5 (0.62) ALOX5PRKDCPARP14DNPH1TNKS
SCHEMBL26512734 0.84 ALOX5 (0.46) ALOX5PRKDCPARP14TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160204345-A1 DITRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-07-14 US disclosed
US-20160204345-A1 DITRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-07-14 US disclosed
US-9166177-B2 Ditriphenylene derivative and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2015-10-20 US disclosed
US-9166177-B2 Ditriphenylene derivative and organic electroluminescent device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2015-10-20 US disclosed
US-20140231754-A1 DITRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Yen, Feng-wen (TW) 2014-08-21 US disclosed
US-20140231754-A1 DITRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Yen, Feng-wen (TW) 2014-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160204345-A1 DITRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME NR2E1, NR0B1, NR2E3 ALOX5 1110/4885PRKDC 4688/4885PARP14 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.