Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15959890 | 0.90 | TRPV1 (0.33) | GRNSORT1KDM4EMAPTTHRB | |
| SCHEMBL16471158 | 0.86 | TRPV1 (0.35) | CTRB1TRPV1 | |
| SCHEMBL25465047 | 0.81 | CTRB1 (0.37) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL25465049 | 0.81 | CTRB1 (0.37) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL26255849 | 0.80 | GRN (0.33) | GRNSORT1CTRB1 | |
| SCHEMBL15959874 | 0.80 | GRN (0.33) | GRNSORT1CA1CA2CA7 | |
| SCHEMBL15959872 | 0.80 | CA1 (0.36) | GRNSORT1CA1CA2CA7 | |
| SCHEMBL15959877 | 0.80 | CYP2C9 (0.39) | GRNSORT1CTRB1 | |
| SCHEMBL15959879 | 0.79 | CA1 (0.50) | CA1CA2CA7GAA | |
| SCHEMBL10076038 | 0.78 | KDM4E (0.34) | GRNSORT1KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235533-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235533-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | DDT, CBR3, HRH4 | GRN 3741/4885SORT1 4463/4885KDM4E 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.