Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15959878 | 0.92 | LMNA (0.37) | LMNASMN1; SMN2MAPK1HTTATM | |
| SCHEMBL28499257 | 0.88 | CA1 (0.44) | LMNASMN1; SMN2MAPK1HTTPRSS1 | |
| SCHEMBL15959891 | 0.84 | PRSS1 (0.33) | PRSS1CTSGCTRB1CMA1KMT2A | |
| SCHEMBL15959893 | 0.81 | CA1 (0.47) | KMT2ACTSK | |
| SCHEMBL12086303 | 0.80 | LMNA (0.44) | LMNASMN1; SMN2MAPK1HTTATM | |
| SCHEMBL15959886 | 0.77 | PRSS1 (0.43) | PRSS1CTSGCTRB1CMA1KMT2A | |
| SCHEMBL15959890 | 0.77 | TRPV1 (0.33) | SMN1; SMN2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL15959872 | 0.75 | CA1 (0.36) | KMT2ACTSK | |
| SCHEMBL15959879 | 0.74 | CA1 (0.50) | KMT2ACTSK | |
| SCHEMBL16471158 | 0.74 | TRPV1 (0.35) | PRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235533-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235533-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | DDT, CBR3, HRH4 | LMNA 1754/4885SMN1; SMN2 1572/4885MAPK1 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.