Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.60 |
| ▸ | BAD | Q92934 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 5/20 | 0.59 |
| ▸ | RXRB | P28702 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169167 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTHSD17B1HSD17B10MEN1 | |
| SCHEMBL13757206 | 0.93 | MAPT (0.65) | SMN1; SMN2MAPTHSD17B1HSD17B10MEN1 | |
| SCHEMBL18364483 | 0.93 | MAPT (0.65) | SMN1; SMN2MAPTHSD17B1HSD17B10MEN1 | |
| SCHEMBL211540 | 0.92 | TSHR (0.71) | SMN1; SMN2MAPTHSD17B1KMT2ATP53 | |
| Calcium SCHEMBL31268578 | 0.90 | TSHR (0.67) | SMN1; SMN2MAPTHSD17B1KMT2ATP53 | |
| Barium SCHEMBL31268595 | 0.90 | TSHR (0.67) | SMN1; SMN2MAPTHSD17B1KMT2ATP53 | |
| Water SCHEMBL29952082 | 0.90 | TSHR (0.67) | SMN1; SMN2MAPTHSD17B1KMT2ATP53 | |
| Potassium SCHEMBL31268570 | 0.90 | TSHR (0.67) | SMN1; SMN2MAPTHSD17B1KMT2ATP53 | |
| Acetic Acid SCHEMBL6439495 | 0.90 | TSHR (0.67) | SMN1; SMN2MAPTHSD17B1KMT2ATP53 | |
| Hydrogen Sulfide SCHEMBL28141612 | 0.90 | TSHR (0.67) | SMN1; SMN2MAPTHSD17B1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353129-B2 | Microporous coordination complex and method of making the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140234624-A1 | MICROPOROUS COORDINATION COMPLEX AND METHOD OF MAKING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234624-A1 | MICROPOROUS COORDINATION COMPLEX AND METHOD OF MAKING THE SAME | CTCF, PCBP1, FHIT | SMN1; SMN2 4624/4885MAPT 2145/4885HSD17B1 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.