SCHEMBL15960434

SCHEMBL15960434

CCC[C@@H]1CC1CC1CC1CCCCCCCCO

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.37
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
PRKCA P17252 4/20 0.32
PRKCE Q02156 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL323066 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL16656319 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL15259625 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL15259592 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL15259591 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL15259575 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL15259624 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL15259577 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL15259595 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1
SCHEMBL15259620 0.92 ALOX5 (0.55) ALOX5LMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140235496-A1 STIMULUS-ELICITED GENOMIC PROFILE MARKERS OF A NEURODEGENERATIVE CONDITION BLANCHETTE ROCKEFELLER NEUROSCIENCES DRIVE (US) 2014-08-21 US disclosed