SCHEMBL15964261

SCHEMBL15964261

CCn1c2ccccc2c2ccc(Cc3ccc4c(c3)c3ccccc3n4C)cc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
LMNA P02545 3/20 0.56
MAPK1 P28482 2/20 0.56
POLB P06746 2/20 0.56
MAPT P10636 10/20 0.54
ALDH1A1 P00352 3/20 0.54
KMT2A Q03164 3/20 0.54
HPGD P15428 3/20 0.54
HSD17B10 Q99714 2/20 0.54
MEN1 O00255 2/20 0.54
HTT P42858 2/20 0.54
HBB P68871 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
TP53 P04637 8/20 0.52
PDE10A Q9Y233 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
THRB P10828 1/20 0.48
PKM P14618 1/20 0.47
NPY5R Q15761 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15964268 0.97 KDM4E (0.56) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL15964273 0.96 KDM4E (0.59) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL15305703 0.94 KDM4E (0.61) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL15625970 0.89 MAPT (0.56) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL12158838 0.89 KDM4E (0.66) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL19762195 0.88 KDM4E (0.54) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL15248355 0.88 KDM4E (0.60) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL17297019 0.86 GPR3 (0.61) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL19769429 0.86 TP53 (0.59) KDM4ELMNAMAPK1POLBMAPT
SCHEMBL19769364 0.84 TP53 (0.57) KDM4ELMNAMAPK1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed