SCHEMBL15964262

SCHEMBL15964262

CCn1c2ccccc2c2ccc(-c3ccc4c(c3)c3ccccc3n4C)cc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.56
MAPT P10636 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
HTT P42858 2/20 0.56
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 1/20 0.56
HBB P68871 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
NPY5R Q15761 5/20 0.53
PTGER4 P35408 4/20 0.51
LMNA P02545 3/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
POLB P06746 2/20 0.49
PKM P14618 1/20 0.49
GPR3 P46089 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15964270 0.97 KDM4E (0.56) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL18213894 0.95 KDM4E (0.61) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL14748530 0.95 KDM4E (0.61) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL15964266 0.94 RXRA (0.56) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL6374760 0.94 KDM4E (0.63) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL17125555 0.91 KDM4E (0.56) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL17809435 0.89 KDM4E (0.58) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL5999686 0.89 KDM4E (0.59) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL14805532 0.89 MAPT (0.69) KDM4EMAPTMEN1KMT2AHTT
SCHEMBL31027168 0.89 MAPT (0.69) KDM4EMAPTMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9985232-B2 Biscarbazole derivative host materials for OLED emissive region IDEMITSU KOSAN CO., LTD. (JP) 2018-05-29 US disclosed
US-9966541-B2 Biscarbazole derivative host materials and green emitter for OLED emissive region IDEMITSU KOSAN CO. LTD. (JP) 2018-05-08 US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-20150243905-A1 BISCARBAZOLE DERIVATIVE HOST MATERIALS AND GREEN EMITTER FOR OLED EMISSIVE REGION IDEMITSU KOSAN CO., LTD. (JP) 2015-08-27 US disclosed
US-20150194621-A1 BISCARBAZOLE DERIVATIVE HOST MATERIALS FOR OLED EMISSIVE REGION UNIVERSAL DISPLAY CORPORATION (US) 2015-07-09 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed