SCHEMBL15964443

SCHEMBL15964443

c1ccc(-c2ccc(-c3ccc(N(c4ccc5c6ccccc6n(-c6ccccc6)c5c4)c4cccc5c4sc4ccccc45)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TNKS O95271 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
ALOX5 P09917 1/20 0.34
HSD17B10 Q99714 1/20 0.33
HDAC4 P56524 1/20 0.30
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15964442 1.00 KDM4E (0.38) KDM4EATML3MBTL1TNKSTNKS2
SCHEMBL12960034 0.98 KDM4E (0.37) KDM4EATML3MBTL1TNKSTNKS2
SCHEMBL24946827 0.98 KDM4E (0.38) KDM4EATML3MBTL1TNKSTNKS2
SCHEMBL18958943 0.96 KDM4E (0.38) KDM4EATML3MBTL1TNKSTNKS2
SCHEMBL23475991 0.95 KDM4E (0.36) KDM4EATML3MBTL1TNKSTNKS2
SCHEMBL24947270 0.95 ATM (0.41) KDM4EATML3MBTL1TNKSTNKS2
SCHEMBL15964441 0.95 ATM (0.41) KDM4EATML3MBTL1TNKSTNKS2
SCHEMBL23476175 0.94 KDM4E (0.35) KDM4EATML3MBTL1ALOX5HSD17B10
SCHEMBL25655370 0.94 ALOX5 (0.41) KDM4EATML3MBTL1ALOX5HSD17B10
SCHEMBL12960065 0.94 KDM4E (0.37) KDM4EATML3MBTL1TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed