Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260605 | 1.00 | PPARG (0.54) | PPARGITGB1ITGA5ITGA4PPARA | |
| SCHEMBL3839905 | 0.86 | PPARG (0.51) | PPARGITGB1ITGA4PPARA | |
| SCHEMBL5250840 | 0.83 | ITGB1 (0.55) | PPARGITGB1ITGA5ITGA4 | |
| SCHEMBL1596607 | 0.82 | PPARG (0.66) | PPARGPPARA | |
| SCHEMBL12704699 | 0.82 | PPARG (0.47) | PPARGITGB1ITGA5PPARA | |
| SCHEMBL3840190 | 0.81 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL5376562 | 0.80 | PPARG (0.45) | PPARG | |
| SCHEMBL3840202 | 0.79 | PPARG (0.44) | PPARG | |
| SCHEMBL5379126 | 0.77 | PPARG (0.48) | PPARGITGB1ITGA4PPARA | |
| SCHEMBL4836084 | 0.77 | ITGB1 (0.61) | ITGB1ITGA5ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919515-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2011-04-05 | — | — | US | disclosed |
| EP-1833805-B1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | ADAMED SP ZOO (PL) | 2010-02-10 | — | — | EP | disclosed |
| US-7312338-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-12-25 | — | — | US | disclosed |
| US-20070219259-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | ADAMED SP. Z O.O. (PL) | 2007-09-20 | — | — | US | disclosed |
| EP-1833805-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | Adamed SP. Z O.O. (PL) | 2007-09-19 | — | — | EP | disclosed |
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-04-19 | — | — | US | disclosed |
| WO-2006067086-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | ADAMED SP. Z O.O. (PL) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | PPARA, PPARD, PPARG | PPARG 3/4885ITGB1 2446/4885ITGA5 2080/4885 |
| US-20070219259-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | PPARA, PPARD, PPARG | PPARG 3/4885ITGB1 2387/4885ITGA5 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.