Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839905 | 0.95 | PPARG (0.51) | PPARGLMNAMEN1KMT2APPARA | |
| SCHEMBL3840202 | 0.92 | PPARG (0.44) | PPARGKCNQ1 | |
| SCHEMBL5376562 | 0.89 | PPARG (0.45) | PPARGLMNAADORA3MAPTKCNQ1 | |
| SCHEMBL5379053 | 0.83 | LMNA (0.39) | LMNAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL5376568 | 0.81 | ALOX5 (0.41) | PPARGLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL3260605 | 0.81 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL1596544 | 0.81 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL13588500 | 0.79 | PPARG (0.43) | PPARG | |
| SCHEMBL5376571 | 0.78 | APP (0.40) | PPARGLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL3840815 | 0.75 | AMY1A (0.55) | LMNAMEN1KMT2AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874745-B1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA RECEPTOR LIGANDS | ADAMED SP ZOO (PL) | 2009-11-11 | — | — | EP | claimed |
| EP-1874745-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA RECEPTOR LIGANDS | Adamed SP. Z O.O. (PL) | 2008-01-09 | — | — | EP | claimed |
| WO-2006077206-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA REZEPTOR LIGANDEN | ADAMED SP. Z O.O. (PL) | 2006-07-27 | — | — | WO | claimed |
| US-20060160868-A1 | 3-Phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2006-07-20 | — | — | US | claimed |
| US-7629370-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z O.O. (PL) | 2009-12-08 | — | — | US | disclosed |
| EP-1874745-B1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA RECEPTOR LIGANDS | ADAMED SP ZOO (PL) | 2009-11-11 | — | — | EP | disclosed |
| EP-1874745-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA RECEPTOR LIGANDS | Adamed SP. Z O.O. (PL) | 2008-01-09 | — | — | EP | disclosed |
| US-7309791-B2 | 3-phenylpropionic acid derivatives | ADAMED SP. Z.O.O (PL) | 2007-12-18 | — | — | US | disclosed |
| US-20070161799-A1 | 3-Phenylpropionic acid derivatives | ADAMED, SP. Z O.O. (PL) | 2007-07-12 | — | — | US | disclosed |
| WO-2006077206-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR- GAMMA REZEPTOR LIGANDEN | ADAMED SP. Z O.O. (PL) | 2006-07-27 | — | — | WO | disclosed |
| US-20060160868-A1 | 3-Phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161799-A1 | 3-Phenylpropionic acid derivatives | PAOX, PPARA, PPARG | PPARG 3/4885LMNA 2813/4885MEN1 4856/4885 |
| US-20060160868-A1 | 3-Phenylpropionic acid derivatives | PPARA, PPARG, PPARD | PPARG 2/4885LMNA 3590/4885MEN1 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.