Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710700 | 0.91 | ALDH1A1 (0.61) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL15965458 | 0.91 | HSD17B10 (0.41) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL10532497 | 0.88 | USP2 (0.59) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL3962083 | 0.88 | USP2 (0.59) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL15965441 | 0.88 | ALDH1A1 (0.64) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL14668934 | 0.87 | HSD17B10 (0.46) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL19295875 | 0.87 | USP2 (0.57) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL10867319 | 0.86 | ALDH1A1 (0.54) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL10712147 | 0.86 | ALDH1A1 (0.54) | HSD17B10ALDH1A1USP2HTTTSHR | |
| SCHEMBL10710795 | 0.86 | HSD17B10 (0.41) | HSD17B10ALDH1A1USP2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |