Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15965484 | 0.91 | HTT (0.39) | ALDH1A1HTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL15965452 | 0.91 | ALDH1A1 (0.46) | ALDH1A1HTTKDM4ESMN1; SMN2HSP90AA1 | |
| SCHEMBL15965504 | 0.90 | KMT2A (0.47) | ALDH1A1HTTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL15965472 | 0.89 | ALDH1A1 (0.40) | ALDH1A1HTTKDM4ESMN1; SMN2HSP90AA1 | |
| SCHEMBL15965463 | 0.89 | KDM4E (0.42) | ALDH1A1HTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL15965464 | 0.87 | ALDH1A1 (0.43) | ALDH1A1HTTKDM4ESMN1; SMN2HSP90AA1 | |
| SCHEMBL15965483 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HTTKDM4ESMN1; SMN2HSP90AA1 | |
| SCHEMBL15965479 | 0.82 | NR4A2 (0.41) | ALDH1A1HTTKDM4EMAPTKMT2A | |
| SCHEMBL15965499 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL15965460 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HTTKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |