Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24343853 | 1.00 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL17598907 | 0.97 | TSHR (0.56) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL9828694 | 0.97 | TSHR (0.56) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL8061825 | 0.95 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL8324832 | 0.92 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL14029328 | 0.91 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL18306258 | 0.91 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL10609160 | 0.88 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL8324661 | 0.88 | TSHR (0.46) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL15508708 | 0.88 | ALDH1A1 (0.64) | MEN1KMT2ATSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |