SCHEMBL15965635

SCHEMBL15965635

Oc1ccc(O)c(/C=N/Nc2nc3ccccc3s2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 15/20 0.60
▸ RAB9A P51151 12/20 0.60
▸ GAA P10253 10/20 0.60
▸ KDM4E B2RXH2 6/20 0.60
▸ SNCA P37840 2/20 0.60
▸ MGAM O43451 1/20 0.58
▸ KMT2A Q03164 11/20 0.57
▸ NPC1 O15118 11/20 0.57
▸ MEN1 O00255 10/20 0.57
▸ MAPK1 P28482 4/20 0.57
▸ LMNA P02545 5/20 0.56
▸ TDP1 Q9NUW8 4/20 0.56
▸ POLB P06746 2/20 0.56
▸ SMN1; SMN2 Q16637 11/20 0.55
▸ NPSR1 Q6W5P4 3/20 0.55
▸ PKM P14618 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ NFKB1 P19838 4/20 0.55
▸ NFKB2 Q00653 4/20 0.55
▸ RELA Q04206 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132582 0.91 MAPT (0.58) MAPTRAB9AGAAKDM4ESNCA
SCHEMBL1132583 0.91 MAPT (0.58) MAPTRAB9AGAAKDM4ESNCA
SCHEMBL1164673 0.82 MBD2 (0.65) MAPTRAB9AGAAKDM4EMGAM
SCHEMBL1164671 0.82 MBD2 (0.65) MAPTRAB9AGAAKDM4EMGAM
SCHEMBL1165592 0.82 MAPT (0.68) MAPTRAB9AGAAKDM4EMGAM
SCHEMBL1165591 0.82 MAPT (0.68) MAPTRAB9AGAAKDM4EMGAM
SCHEMBL15494570 0.81 MAPT (0.61) MAPTRAB9AGAAKDM4EKMT2A
SCHEMBL21010612 0.81 MAPT (0.68) MAPTRAB9AGAAKDM4EMGAM
SCHEMBL13779288 0.81 MAPT (0.75) MAPTRAB9AGAAKDM4EMGAM
SCHEMBL17933603 0.80 MAPT (0.52) MAPTRAB9AGAAKDM4EMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9447059-B2 Intermediate for manufacture of polymerizable compound and process for manufacture thereof ZEON CORPORATION (JP) 2016-09-20 — — US disclosed
US-9447059-B2 Intermediate for manufacture of polymerizable compound and process for manufacture thereof ZEON CORPORATION (JP) 2016-09-20 — — US disclosed
US-9207362-B2 Copolymer, optically anisotropic substance, and oriented polymer film ZEON CORPORATION (JP) 2015-12-08 — — US disclosed
US-9207362-B2 Copolymer, optically anisotropic substance, and oriented polymer film ZEON CORPORATION (JP) 2015-12-08 — — US disclosed
US-20150232625-A1 COPOLYMER, OPTICALLY ANISOTROPIC SUBSTANCE, AND ORIENTED POLYMER FILM ZEON CORPORATION (JP) 2015-08-20 — — US disclosed
US-20150232625-A1 COPOLYMER, OPTICALLY ANISOTROPIC SUBSTANCE, AND ORIENTED POLYMER FILM ZEON CORPORATION (JP) 2015-08-20 — — US disclosed
US-20140235857-A1 INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF ZEON CORPORATION (JP) 2014-08-21 — — US disclosed
US-20140235857-A1 INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF ZEON CORPORATION (JP) 2014-08-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235857-A1 INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF COASY, CYBA, CYP1B1 MAPT 2005/4885RAB9A 3416/4885GAA 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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