SCHEMBL13779288

SCHEMBL13779288

Oc1ccc(/C=N/Nc2nc3ccccc3s2)cc1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 14/20 0.75
▸ RAB9A P51151 12/20 0.75
▸ NPC1 O15118 12/20 0.75
▸ KMT2A Q03164 12/20 0.75
▸ GAA P10253 11/20 0.75
▸ MEN1 O00255 11/20 0.75
▸ KDM4E B2RXH2 5/20 0.75
▸ MAPK1 P28482 3/20 0.75
▸ SMN1; SMN2 Q16637 10/20 0.64
▸ TP53 P04637 2/20 0.64
▸ NPSR1 Q6W5P4 3/20 0.60
▸ POLB P06746 2/20 0.60
▸ TDP1 Q9NUW8 2/20 0.60
▸ PAX8 Q06710 1/20 0.60
▸ MGAM O43451 1/20 0.57
▸ NFKB1 P19838 5/20 0.56
▸ NFKB2 Q00653 5/20 0.56
▸ RELA Q04206 5/20 0.56
▸ LMNA P02545 4/20 0.56
▸ HPGD P15428 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1165591 0.85 MAPT (0.68) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL1165592 0.85 MAPT (0.68) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL21010612 0.85 MAPT (0.68) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL1231354 0.82 MAPT (0.70) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL1231353 0.82 MAPT (0.70) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL22103769 0.81 MAPT (0.64) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL15965635 0.81 MAPT (0.60) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL1164671 0.81 MBD2 (0.65) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL1164673 0.81 MBD2 (0.65) MAPTRAB9ANPC1KMT2AGAA
SCHEMBL1132582 0.80 MAPT (0.58) MAPTRAB9ANPC1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223746-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2023-08-09 — — EP disclosed
EP-3483141-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2023-07-19 — — EP disclosed
US-10647794-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic material ZEON CORPORATION (JP) 2020-05-12 — — US disclosed
EP-2703385-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2017-09-20 — — EP disclosed
US-9447059-B2 Intermediate for manufacture of polymerizable compound and process for manufacture thereof ZEON CORPORATION (JP) 2016-09-20 — — US disclosed
US-9447059-B2 Intermediate for manufacture of polymerizable compound and process for manufacture thereof ZEON CORPORATION (JP) 2016-09-20 — — US disclosed
US-20160145363-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORPORATION (JP) 2016-05-26 — — US disclosed
US-20160145363-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORPORATION (JP) 2016-05-26 — — US disclosed
US-9207360-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body ZENO CORPORATION (JP) 2015-12-08 — — US disclosed
US-9207360-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body ZENO CORPORATION (JP) 2015-12-08 — — US disclosed
US-20140235857-A1 INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF ZEON CORPORATION (JP) 2014-08-21 — — US disclosed
US-20140235857-A1 INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF ZEON CORPORATION (JP) 2014-08-21 — — US disclosed
US-20140142266-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY ZEON CORPORATION (JP) 2014-05-22 — — US disclosed
US-20140142266-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY ZEON CORPORATION (JP) 2014-05-22 — — US disclosed
US-20090176773-A1 Non-Peptidic Inhibitors of AKAP/PKA Interaction FORSCHUNGSVERBUND BERLIN E.V. (DE) 2009-07-09 — — US disclosed
US-20090176773-A1 Non-Peptidic Inhibitors of AKAP/PKA Interaction FORSCHUNGSVERBUND BERLIN E.V. (DE) 2009-07-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235857-A1 INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF COASY, CYBA, CYP1B1 MAPT 2005/4885RAB9A 3416/4885NPC1 3093/4885
US-20090176773-A1 Non-Peptidic Inhibitors of AKAP/PKA Interaction PRKCH, AIP, PRKCE MAPT 3655/4885RAB9A 959/4885NPC1 1716/4885
US-20160145363-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL F12, C1S, C5 MAPT 347/4885RAB9A 4104/4885NPC1 2910/4885
US-10647794-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic material C1S, F12, C5 MAPT 564/4885RAB9A 4226/4885NPC1 2766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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