Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132254 | 0.87 | POLB (0.66) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL1132255 | 0.87 | POLB (0.66) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL8416040 | 0.84 | MAPT (0.65) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL8416037 | 0.84 | MAPT (0.65) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL1132162 | 0.83 | POLB (0.65) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL1132160 | 0.83 | POLB (0.65) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL4668751 | 0.74 | MAPT (0.74) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL4668750 | 0.74 | MAPT (0.74) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL9427836 | 0.74 | POLB (0.62) | POLBEIF4HMAPTGAAMAPK1 | |
| SCHEMBL8416093 | 0.74 | POLB (0.62) | POLBEIF4HMAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447059-B2 | Intermediate for manufacture of polymerizable compound and process for manufacture thereof | ZEON CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-9447059-B2 | Intermediate for manufacture of polymerizable compound and process for manufacture thereof | ZEON CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-20140235857-A1 | INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF | ZEON CORPORATION (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140235857-A1 | INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF | ZEON CORPORATION (JP) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235857-A1 | INTERMEDIATE FOR MANUFACTURE OF POLYMERIZABLE COMPOUND AND PROCESS FOR MANUFACTURE THEREOF | COASY, CYBA, CYP1B1 | POLB 3432/4885EIF4H 1133/4885MAPT 2005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.