SCHEMBL4668750

SCHEMBL4668750

Oc1cc(N(c2ccccc2)c2ccccc2)ccc1/C=N/N(c1ccccc1)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.74
GAA P10253 6/20 0.74
MAPK1 P28482 3/20 0.74
HTT P42858 3/20 0.74
POLB P06746 2/20 0.62
EIF4H Q15056 1/20 0.62
ALDH1A1 P00352 10/20 0.49
KDM4E B2RXH2 6/20 0.49
HPGD P15428 2/20 0.46
ALOX12 P18054 1/20 0.46
MEN1 O00255 7/20 0.46
KMT2A Q03164 7/20 0.46
LMNA P02545 5/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TDP1 Q9NUW8 4/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
USP2 O75604 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4668751 1.00 MAPT (0.74) MAPTGAAMAPK1HTTPOLB
SCHEMBL4669503 0.86 MAPT (0.72) MAPTGAAMAPK1HTTPOLB
SCHEMBL4669501 0.86 MAPT (0.72) MAPTGAAMAPK1HTTPOLB
SCHEMBL4668743 0.85 MAPT (1.00) MAPTGAAMAPK1HTTPOLB
SCHEMBL4668744 0.85 MAPT (1.00) MAPTGAAMAPK1HTTPOLB
SCHEMBL1132254 0.84 POLB (0.66) MAPTGAAMAPK1HTTPOLB
SCHEMBL1132255 0.84 POLB (0.66) MAPTGAAMAPK1HTTPOLB
SCHEMBL9876003 0.81 MAPT (0.55) MAPTGAAMAPK1HTTPOLB
SCHEMBL1132160 0.80 POLB (0.65) MAPTGAAMAPK1HTTPOLB
SCHEMBL1132162 0.80 POLB (0.65) MAPTGAAMAPK1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443365-B1 Organophotoreceptor with charge transport material having an amino-substituted hydrazone group and an epoxy group SAMSUNG ELECTRONICS CO LTD (KR) 2008-02-20 EP disclosed
US-7183028-B2 Organophotoreceptor with novel charge transport compounds having an epoxy group SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-02-27 US disclosed
US-20040157145-A1 Organophotoreceptor with novel charge transport compounds having an epoxy group S-PRINTING SOLUTION CO., LTD. (KR) 2004-08-12 US disclosed
EP-1443365-A1 Organophotoreceptor with charge transport material having an amino-substituted hydrazone group and an epoxy group Samsung Electronics Co., Ltd. (KR) 2004-08-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040157145-A1 Organophotoreceptor with novel charge transport compounds having an epoxy group SLC43A1, SLC16A3, SLC26A3 MAPT 4115/4885GAA 2662/4885MAPK1 3203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.