SCHEMBL15965693

SCHEMBL15965693

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccc5oc6ccc(-c7ccccc7-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)cc6c5c4)ccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
EDNRA P25101 2/20 0.35
EDNRB P24530 1/20 0.35
HDAC4 P56524 1/20 0.34
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
ALDH1A1 P00352 3/20 0.33
PTGER4 P35408 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
BRCA1 P38398 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965688 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL15965689 0.97 KDM4E (0.44) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL20097827 0.97 KDM4E (0.44) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL15965694 0.97 KDM4E (0.44) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL16482011 0.97 L3MBTL1 (0.44) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL15965719 0.97 KDM4E (0.44) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL15965720 0.96 KDM4E (0.50) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL13309687 0.95 KDM4E (0.51) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL20633677 0.95 KDM4E (0.51) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL5028236 0.95 KDM4E (0.51) KDM4EL3MBTL1ATMSIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140231772-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 US disclosed
US-20140231772-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 US disclosed