Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18383213 | 0.98 | TSHR (0.50) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL15247542 | 0.88 | MAPT (0.56) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13363917 | 0.87 | MAPT (0.61) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29871430 | 0.84 | MAPT (0.58) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16267302 | 0.83 | PLA2G7 (0.40) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11331023 | 0.83 | NPSR1 (0.47) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18015899 | 0.83 | SIRT2 (0.45) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18383359 | 0.83 | SIRT2 (0.49) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29257205 | 0.82 | MAPT (0.56) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL304152 | 0.82 | MAPT (0.56) | TSHRCYP3A4CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390365-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-20140234238-A1 | BENZODIOXEPIN-3-ONE COMPOUNDS AS DYES OR AS FLUORESCENT EMITTERS | MERCK PATENT GMBH (DE) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234238-A1 | BENZODIOXEPIN-3-ONE COMPOUNDS AS DYES OR AS FLUORESCENT EMITTERS | OXER1, OCIAD1, OCIAD2 | TSHR 4167/4885CYP3A4 149/4885CYP1A2 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.