Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 20/20 | 0.74 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.60 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.60 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345726 | 0.93 | FGFR2 (0.71) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345725 | 0.93 | FGFR2 (0.71) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL17899398 | 0.92 | FGFR2 (0.69) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL16241631 | 0.90 | FGFR2 (0.63) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL17772430 | 0.89 | FGFR2 (0.66) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15966918 | 0.88 | FGFR2 (0.65) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL20644838 | 0.88 | FGFR2 (0.65) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345562 | 0.87 | FGFR2 (0.59) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15138367 | 0.86 | FGFR2 (0.70) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345615 | 0.86 | FGFR2 (0.87) | FGFR2FGFR1FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657233-B1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2014-08-27 | — | — | EP | claimed |