Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 20/20 | 0.71 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.61 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.61 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345726 | 1.00 | FGFR2 (0.71) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL17772430 | 0.96 | FGFR2 (0.66) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15966877 | 0.93 | FGFR2 (0.74) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL17899398 | 0.91 | FGFR2 (0.69) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15966918 | 0.87 | FGFR2 (0.65) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL20644838 | 0.87 | FGFR2 (0.65) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345775 | 0.87 | FGFR2 (0.58) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345774 | 0.87 | FGFR2 (0.58) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL17902990 | 0.86 | FGFR1 (0.69) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15138367 | 0.86 | FGFR2 (0.70) | FGFR2FGFR1FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9108973-B2 | 3,5-disubstituted alkynylbenzene compound and salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-08-18 | — | — | US | claimed |
| US-20140343035-A1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | TAIHO PHARMACEUTICAL CO.,LTD. (JP) | 2014-11-20 | — | — | US | claimed |
| EP-2657233-B1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2014-08-27 | — | — | EP | claimed |
| EP-2657233-A1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2013-10-30 | — | — | EP | claimed |
| US-11975002-B2 | Preparation and composition for treatment of malignant tumors | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-05-07 | — | — | US | disclosed |
| US-11883404-B2 | Preparation and composition for treatment of malignant tumors | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2024-01-30 | — | — | US | disclosed |
| US-11690843-B2 | — | — | 2023-07-04 | — | — | US | disclosed |
| US-10894048-B2 | Antitumor drug for intermittent administration of FGFR inhibitor | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-01-19 | — | — | US | disclosed |
| US-10835536-B2 | Therapeutic agent for FGFR inhibitor-resistant cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| US-10835536-B2 | Therapeutic agent for FGFR inhibitor-resistant cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| US-20200281927-A1 | PREPARATION AND COMPOSITION FOR TREATMENT OF MALIGNANT TUMORS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-09-10 | — | — | US | disclosed |
| EP-3023101-B1 | THERAPEUTIC AGENT FOR FGFR INHIBITOR-RESISTANT CANCER | TAIHO PHARMACEUTICAL CO LTD (JP) | 2020-08-19 | — | — | EP | disclosed |
| US-9108973-B2 | 3,5-disubstituted alkynylbenzene compound and salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-9108973-B2 | 3,5-disubstituted alkynylbenzene compound and salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-9108973-B2 | 3,5-disubstituted alkynylbenzene compound and salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20140343035-A1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | TAIHO PHARMACEUTICAL CO.,LTD. (JP) | 2014-11-20 | — | — | US | disclosed |
| US-20140343035-A1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | TAIHO PHARMACEUTICAL CO.,LTD. (JP) | 2014-11-20 | — | — | US | disclosed |
| US-20140343035-A1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | TAIHO PHARMACEUTICAL CO.,LTD. (JP) | 2014-11-20 | — | — | US | disclosed |
| EP-2657233-B1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2014-08-27 | — | — | EP | disclosed |
| EP-2657233-A1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2013-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281927-A1 | PREPARATION AND COMPOSITION FOR TREATMENT OF MALIGNANT TUMORS | FGFR3, FGFR1, FGFR4 | FGFR2 4/4885FGFR1 2/4885FGFR4 3/4885 |
| US-11690843-B2 | — | FGFR3, FGFR1, FGFR4 | FGFR2 4/4885FGFR1 2/4885FGFR4 3/4885 |
| US-11975002-B2 | Preparation and composition for treatment of malignant tumors | FGFR3, FGFR1, FGFR4 | FGFR2 4/4885FGFR1 2/4885FGFR4 3/4885 |
| US-11883404-B2 | Preparation and composition for treatment of malignant tumors | FGFR3, FGFR1, FGFR4 | FGFR2 4/4885FGFR1 2/4885FGFR4 3/4885 |
| US-10894048-B2 | Antitumor drug for intermittent administration of FGFR inhibitor | FGFR1, FGFR3, FGFR2 | FGFR2 3/4885FGFR1 1/4885FGFR4 4/4885 |
| US-20140343035-A1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | NFXL1, ZFX, CXXC5 | FGFR2 1329/4885FGFR1 626/4885FGFR4 1114/4885 |
| US-10835536-B2 | Therapeutic agent for FGFR inhibitor-resistant cancer | FGFR1, FGFR3, FGFR4 | FGFR2 4/4885FGFR1 1/4885FGFR4 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.