Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 7/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17305883 | 1.00 | CYP2D6 (0.35) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15966894 | 1.00 | CYP2D6 (0.35) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15976654 | 0.87 | CYP2D6 (0.38) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1155771 | 0.87 | CYP2D6 (0.38) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17291887 | 0.87 | CYP2D6 (0.38) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15966854 | 0.87 | CYP2D6 (0.35) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15966855 | 0.87 | CYP2D6 (0.35) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16401546 | 0.87 | CYP2D6 (0.35) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16401497 | 0.86 | CYP2D6 (0.34) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16401496 | 0.86 | CYP2D6 (0.34) | CYP2D6HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932361-B2 | Convenient process for the preparation of statins | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2018-04-03 | — | — | US | disclosed |
| EP-2867231-B1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F I S - FABBRICA ITALIANA SINTETICI S P A (IT) | 2017-01-04 | — | — | EP | disclosed |
| US-20160200744-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2016-07-14 | — | — | US | disclosed |
| US-9315470-B2 | Convenient process for the preparation of statins | F.I.S.—Fabbrica Italiana Sintetiei S.p.A. (IT) | 2016-04-19 | — | — | US | disclosed |
| US-20150344439-A1 | Convenient Process for the Preparation of Statins | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2015-12-03 | — | — | US | disclosed |
| EP-2867231-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S.- Fabbrica Italiana Sintetici S.p.A. (IT) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014128022-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2014-08-28 | — | — | WO | disclosed |
| EP-2769979-A1 | Process for the preparation of key intermediates for the synthesis of Statins | F.I.S.- Fabbrica Italiana Sintetici S.p.A. (IT) | 2014-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344439-A1 | Convenient Process for the Preparation of Statins | HMGCR, PCSK9, FDPS | CYP2D6 144/4885HDAC3 969/4885HDAC1 2044/4885 |
| US-20160200744-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | HMGCR, PCSK9, FDPS | CYP2D6 144/4885HDAC3 969/4885HDAC1 2044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.