Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967160 | 0.95 | SLC6A9 (0.65) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| SCHEMBL15967134 | 0.90 | SLC6A9 (0.64) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| SCHEMBL15967238 | 0.89 | SLC6A9 (0.63) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| SCHEMBL15966945 | 0.89 | SLC6A9 (0.65) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| SCHEMBL15967382 | 0.89 | SLC6A9 (0.65) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| SCHEMBL6103726 | 0.89 | SLC6A9 (0.78) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| SCHEMBL15967345 | 0.88 | SLC6A9 (0.77) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| Hydrochloric Acid SCHEMBL15967064 | 0.88 | SLC6A9 (0.76) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| SCHEMBL15967336 | 0.87 | SLC6A9 (0.67) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 | |
| SCHEMBL15967056 | 0.86 | SLC6A9 (0.65) | SLC6A9KCNH2CYP2D6CYP3A4SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |