⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16241088 | 0.82 | CACNA1H (0.43) | — | |
| SCHEMBL16249228 | 0.82 | CACNA1H (0.43) | — | |
| SCHEMBL15049934 | 0.81 | BCHE (0.37) | — | |
| SCHEMBL22342307 | 0.74 | ATM (0.47) | — | |
| SCHEMBL15967367 | 0.73 | CYP2C19 (0.39) | — | |
| SCHEMBL28105023 | 0.72 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL28104672 | 0.72 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL10002476 | 0.72 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL25024449 | 0.72 | S1PR5 (0.40) | — | |
| SCHEMBL15967265 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |