Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 16/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967056 | 0.92 | SLC6A9 (0.65) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL15967312 | 0.90 | SLC6A9 (0.65) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL15967293 | 0.90 | SLC6A9 (0.64) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL15967382 | 0.89 | SLC6A9 (0.65) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL15967130 | 0.89 | SLC6A9 (0.58) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL15967232 | 0.89 | SLC6A9 (0.60) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL6103741 | 0.88 | SLC6A9 (0.78) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL15967313 | 0.88 | SLC6A9 (0.65) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL15967336 | 0.88 | SLC6A9 (0.67) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 | |
| SCHEMBL15967345 | 0.88 | SLC6A9 (0.77) | SLC6A9KCNH2CYP2D6SLC6A5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |