Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | ACACB | O00763 | 14/20 | 0.46 |
| ▸ | ACACA | Q13085 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15968221 | 0.88 | ACACB (0.44) | ESR1ESR2ACACBACACA | |
| SCHEMBL15968219 | 0.86 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL15969486 | 0.86 | ESR1 (0.53) | ESR1ESR2ACACBACACA | |
| SCHEMBL15968791 | 0.85 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL15969008 | 0.85 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL15969365 | 0.85 | ACACB (0.51) | ACACBACACA | |
| SCHEMBL15969320 | 0.85 | ACACB (0.56) | ACACBACACA | |
| SCHEMBL14908405 | 0.84 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL15969362 | 0.84 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL15969310 | 0.84 | ACACB (0.45) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133129-B2 | Bicyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-09-15 | — | — | US | disclosed |
| EP-2772485-A1 | BICYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-09-03 | — | — | EP | disclosed |
| US-20140243310-A1 | BICYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243310-A1 | BICYCLIC COMPOUND | BICRA, NR3C2, CYP11B2 | ESR1 2402/4885ESR2 2876/4885ACACB 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.