Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287190 | 0.87 | ALDH1A1 (0.50) | TDP1CYP1A2CYP3A4PTGS2IDO1 | |
| Bromide SCHEMBL30083679 | 0.84 | ALDH1A1 (0.47) | TDP1CYP1A2CYP3A4PTGS2IDO1 | |
| SCHEMBL3183189 | 0.81 | TAAR1 (0.46) | TAAR1TDP1CYP1A2CYP3A4PTGS2 | |
| Diphenylamine SCHEMBL28096837 | 0.76 | HSD17B10 (0.71) | TAAR1TDP1CYP1A2CYP3A4PTGS2 | |
| SCHEMBL28415827 | 0.75 | TDP1 (0.42) | TAAR1TDP1CYP1A2CYP3A4PTGS2 | |
| SCHEMBL6864584 | 0.72 | ALDH1A1 (0.47) | TAAR1TDP1CYP1A2CYP3A4PTGS2 | |
| 4-Aminophenol SCHEMBL9770027 | 0.72 | CYP3A4 (0.52) | TAAR1TDP1CYP1A2CYP3A4LMNA | |
| SCHEMBL11119765 | 0.71 | ALDH1A1 (0.39) | TAAR1TDP1CYP1A2CYP3A4PTGS2 | |
| SCHEMBL28253198 | 0.70 | — | — | |
| Ethylenediamine SCHEMBL1701811 | 0.70 | TSHR (0.70) | TAAR1TDP1CYP1A2CYP3A4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10411252-B2 | Positive electrode composition, a positive electrode of a lithiumion electrochemical cell, and a method of forming the positive electrode | GM Global Technology Operations LLC (US) | 2019-09-10 | — | — | US | disclosed |
| US-20170229705-A1 | POSITIVE ELECTRODE COMPOSITION, A POSITIVE ELECTRODE OF A LITHIUMION ELECTROCHEMICAL CELL, AND A METHOD OF FORMING THE POSITIVE ELECTRODE | GM Global Technology Operations LLC (US) | 2017-08-10 | — | — | US | disclosed |
| US-20140242452-A1 | LITHIUM ION BATTERY | GM Global Technology Operations LLC (US) | 2014-08-28 | — | — | US | disclosed |