Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | HPGD | P15428 | 4/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | FHIT | P49789 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 6/20 | 0.62 |
| ▸ | BCHE | P06276 | 5/20 | 0.62 |
| ▸ | STS | P08842 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15973184 | 0.96 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL15973990 | 0.94 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL15971776 | 0.88 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL11044109 | 0.87 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL15971987 | 0.87 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL25799533 | 0.86 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL15971892 | 0.86 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL31706571 | 0.86 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL13799892 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10503978 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958906-A1 | 3-SUBSTITUTED-6H-BENZO[C]CHROMEN-6-ONES AND 3-SUBSTITUTED-7,8,9,10-TETRAHYDRO-6H-BENZO[C]CHROMEN-6-ONES AGAINST SENILE DEMENTIA | Nobel Ilaç Sanayii Ve Ticaret A.S. (TR) | 2015-12-30 | — | — | EP | claimed |
| WO-2014129989-A1 | 3-SUBSTITUTED-6H-BENZO[C]CHROMEN-6-ONES AND 3-SUBSTITUTED-7,8,9,10-TETRAHYDRO-6H-BENZO[C]CHROMEN-6-ONES AGAINST SENILE DEMENTIA | FARGEM FARMASÖTİK ARAŞTIRMA GELİŞTİRME MERKEZİ SANAYİ VE TİCARET A.Ş. (TR) | 2014-08-28 | — | — | WO | claimed |