SCHEMBL159753

SCHEMBL159753

NC(=O)C=Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.67
HDAC3 O15379 2/20 0.67
HDAC4 P56524 2/20 0.67
HDAC1 Q13547 2/20 0.67
HDAC2 Q92769 2/20 0.67
HDAC8 Q9BY41 2/20 0.67
HDAC6 Q9UBN7 2/20 0.67
PLIN1 O60240 2/20 0.67
LMNA P02545 2/20 0.67
RECQL P46063 2/20 0.67
PLIN5 Q00G26 2/20 0.67
ABHD5 Q8WTS1 2/20 0.67
ALDH1A1 P00352 2/20 0.67
F3 P13726 2/20 0.67
TNKS O95271 1/20 0.67
HCAR2 Q8TDS4 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC10 Q969S8 1/20 0.67
HDAC11 Q96DB2 1/20 0.67
TNKS2 Q9H2K2 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3239009 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL20303734 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL649508 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL20303732 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL29966141 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
Hydrochloric Acid SCHEMBL31595739 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1584715 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1584710 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
Ammonia Solution, Strong SCHEMBL28968010 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL28141693 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5812 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 EP claimed
EP-4713340-A2 COMPOSITIONS AND METHODS FOR PEPTIDE-BASED MODULATORS OF HUMAN PAPILLOMAVIRUS ONCOPROTEIN E6 Calico Life Sciences LLC (US) 2026-03-25 EP claimed
EP-4049841-B1 HYBRID RESIN COMPOSITION CUBICURE GMBH (AT) 2026-03-18 EP claimed
CN-119528637-B Microorganism-inorganic combined fertilizer and preparation method thereof 重庆大学 2026-02-27 CN claimed
US-12552755-B2 Cinnamic amide derivative having FXR activating effect, pharmaceutical composition containing the same as active ingredient, and method for preparing the same KYUNGSUNG UNIVERSITY INDUSTRY COOPERATION FOUNDATION (KR) 2026-02-17 US claimed
US-20260040695-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NEWSOUTH INNOVATIONS PTY LTD (AU) 2026-02-05 US claimed
EP-4646188-A1 INJECTABLE FORMULATION COMPRISING A BIOPHARMACEUTICAL AGENT AND A POLYACRYLAMIDE-BASED COPOLYMER The Board of Trustees of the Leland Stanford Junior University (US) 2025-11-12 EP claimed
US-12451489-B2 Anode material, preparation method thereof and battery BTR NEW MATERIAL GROUP CO., LTD. (CN) 2025-10-21 US claimed
WO-2025202518-A1 MEASURE OF A QUINOLINATE AND TRYPTOPHAN CONCENTRATION Institut National de la Santé et de la Recherche Médicale (FR) 2025-10-02 WO claimed
US-20250273679-A1 ANODE MATERIAL, PREPARATION METHOD THEREOF AND BATTERY BTR NEW MATERIAL GROUP CO., LTD. (CN) 2025-08-28 US claimed
US-4883653-A PLASTICS AND COSMETICS, SUNSCREENS OLIN CORPORATION (US) 1989-11-28 US claimed
US-4863963-A 5-A-REDUCTASE INHIBITOR ONO PHARMACEUTICAL CO., LTD. (JP) 1989-09-05 US claimed
CN-1035034-A The improvement of avian control NAT RES DEV (GB) 1989-08-30 CN claimed
EP-0321208-A1 Improvements in or relating to avian control NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1989-06-21 EP claimed
EP-0294937-A2 Novel cinnamoylamide derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-12-14 EP claimed
EP-0291247-A2 Novel cinnamoylamide derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-11-17 EP claimed
EP-0290133-A2 Ternary photoinitiator system for addition polymerization MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-09 EP claimed
EP-0094283-B1 SUSTAINED-RELEASE THEOPHYLLIN DRUG FORMULATION LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1985-11-21 EP claimed
US-4512994-A ANTIASTHMATIC AGENTS;BRONCHO DILATORS LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1985-04-23 US claimed
EP-0094283-A1 Sustained-release theophyllin drug formulation LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1983-11-16 EP claimed