SCHEMBL649508

SCHEMBL649508

NC(=O)/C=C/c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.67
HDAC3 O15379 2/20 0.67
HDAC4 P56524 2/20 0.67
HDAC1 Q13547 2/20 0.67
HDAC2 Q92769 2/20 0.67
HDAC8 Q9BY41 2/20 0.67
HDAC6 Q9UBN7 2/20 0.67
PLIN1 O60240 2/20 0.67
LMNA P02545 2/20 0.67
RECQL P46063 2/20 0.67
PLIN5 Q00G26 2/20 0.67
ABHD5 Q8WTS1 2/20 0.67
ALDH1A1 P00352 2/20 0.67
F3 P13726 2/20 0.67
TNKS O95271 1/20 0.67
HCAR2 Q8TDS4 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC10 Q969S8 1/20 0.67
HDAC11 Q96DB2 1/20 0.67
TNKS2 Q9H2K2 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3239009 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL20303734 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL159753 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL20303732 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL29966141 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
Hydrochloric Acid SCHEMBL31595739 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1584715 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1584710 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
Ammonia Solution, Strong SCHEMBL28968010 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL28141693 0.98 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4435 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113679717-B Methods for inhibiting fascin 康奈尔大学 2026-05-22 CN claimed
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 EP claimed
CN-119528637-B Microorganism-inorganic combined fertilizer and preparation method thereof 重庆大学 2026-02-27 CN claimed
EP-4605088-A1 MOLECULAR GLUE DEGRADER COMPOUNDS AND USES THEREOF Novartis AG (CH) 2025-08-27 EP claimed
CN-120058679-A Cinnamamide 3CL protease covalent inhibitor, preparation method thereof and application thereof in preparation of anti-coronavirus drugs 陕西科技大学 2025-05-30 CN claimed
EP-4557952-A1 TRIGEMINAL CUE FOR WILDLIFE REPELLENTS The United States of America, as represented by the Secretary of Agriculture (US) 2025-05-28 EP claimed
CN-119978813-A Shedding controllable bird repellent material, preparation method and application 国网冀北电力有限公司廊坊供电公司 2025-05-13 CN claimed
CN-119930529-A Cinnamoyl triazole compound, preparation method thereof and application thereof in neuroprotection 中国医学科学院医药生物技术研究所 2025-05-06 CN claimed
CN-119859265-A Polybenzoxazole-based or polyimide-based precursor, copolymer thereof, and positive photosensitive composition containing same 德山新勒克斯有限公司 2025-04-22 CN claimed
CN-119410557-B Rhodococcus ruber and application thereof 天津科技大学 2025-04-08 CN claimed
EP-0094283-A1 Sustained-release theophyllin drug formulation LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1983-11-16 EP claimed
EP-0091726-A2 5-Substituted 1,2,4-oxadiazole derivatives, their preparation and pharmaceutical compositions containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-19 EP claimed
EP-0071926-A1 New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-02-16 EP claimed
US-4105653-A HETERYL-AZO-PHENYL DISPERSE DYESTUFFS CONTAINING A Z-SUBSTITUTED BENZOLYLOXYALKYL RADICAL, WHEREIN Z IS 2-CYANOVINYL 2-CYANOETHYL OR 2-CHLORO-2-CYANOETHYL PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-08-08 US claimed
US-4101543-A DYES FOR CELLULOSE ACETATES, AROMATIC POLYESTERS OR POLYAMIDES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 US claimed
US-4085099-A AZO DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-04-18 US claimed
US-4014892-A ANTHELMINTICS AMERICAN CYANAMID COMPANY (US) 1977-03-29 US claimed
US-4013632-A SYNTHETIC FIBERS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-22 US claimed
US-4010151-A Water insoluble mono azo and disazo dyes containing cinnamonitrile group PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-01 US claimed
US-4008213-A WATER INSOLUBLE UGINE KUHLMANN (FR) 1977-02-15 US claimed