Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13129834 | 1.00 | LMNA (0.55) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL10608406 | 0.93 | LMNA (0.57) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL29220835 | 0.86 | CYP2D6 (0.51) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL29220838 | 0.86 | CYP2D6 (0.51) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL13130039 | 0.85 | LMNA (0.43) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL15975416 | 0.85 | LMNA (0.43) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL22677447 | 0.85 | SSTR1 (0.51) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL22677754 | 0.85 | SSTR1 (0.51) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL22677688 | 0.84 | CYP2D6 (0.51) | LMNAKMT2APOLBPTPN1PTPN2 | |
| SCHEMBL8831104 | 0.84 | POLB (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815239-B2 | Glycoconjugates and use thereof as vaccine against Shigella flexneri serotype 3a and X | INSTITUT PASTEUR (FR) | 2014-08-26 | — | — | US | disclosed |