Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | GJA1 | P17302 | 2/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.42 |
| ▸ | CDC25B | P30305 | 4/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975405 | 0.94 | GJB2 (0.47) | GJB2NT5EGJA1SSTR1SSTR2 | |
| SCHEMBL15975421 | 0.93 | GJB2 (0.49) | GJB2NT5EGJA1SSTR1SSTR2 | |
| SCHEMBL13129827 | 0.93 | GJB2 (0.50) | GJB2NT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL13129876 | 0.93 | GJB2 (0.50) | GJB2NT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL13129789 | 0.93 | GJB2 (0.50) | GJB2NT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL13129826 | 0.93 | GJB2 (0.50) | GJB2NT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL15975388 | 0.93 | GJB2 (0.50) | GJB2NT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL15975401 | 0.90 | GJB2 (0.49) | GJB2NT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL15975403 | 0.89 | GJB2 (0.46) | GJB2NT5EGJA1SSTR1SSTR2 | |
| SCHEMBL15975415 | 0.89 | GJB2 (0.48) | GJB2NT5ESSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815239-B2 | Glycoconjugates and use thereof as vaccine against Shigella flexneri serotype 3a and X | INSTITUT PASTEUR (FR) | 2014-08-26 | — | — | US | disclosed |