Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498248 | 0.92 | CA2 (0.42) | CA2CA9CA1ALDH1A1CA12 | |
| SCHEMBL13129980 | 0.90 | CA2 (0.41) | CA2CA9CA1ALDH1A1CA12 | |
| SCHEMBL13129913 | 0.90 | CA2 (0.41) | CA2CA9CA1ALDH1A1CA12 | |
| SCHEMBL21418889 | 0.82 | CA2 (0.39) | CA2CA9CA1ALDH1A1LMNA | |
| SCHEMBL15948718 | 0.82 | CA2 (0.39) | CA2CA9CA1ALDH1A1LMNA | |
| SCHEMBL17972412 | 0.79 | CA2 (0.36) | CA2CA9CA1ALDH1A1HPGD | |
| SCHEMBL12148917 | 0.78 | CA2 (0.40) | CA2CA9CA1ALDH1A1CA12 | |
| SCHEMBL20419296 | 0.78 | CA2 (0.36) | CA2CA9CA1ALDH1A1LMNA | |
| SCHEMBL12150836 | 0.78 | CA2 (0.40) | CA2CA9CA1ALDH1A1CA12 | |
| SCHEMBL17976917 | 0.78 | CA2 (0.40) | CA2CA9CA1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815239-B2 | Glycoconjugates and use thereof as vaccine against Shigella flexneri serotype 3a and X | INSTITUT PASTEUR (FR) | 2014-08-26 | — | — | US | disclosed |