Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15356674 | 1.00 | NPC1 (0.33) | NPC1RAB9ALMNAADORA3MAP3K5 | |
| SCHEMBL10278832 | 1.00 | NPC1 (0.33) | NPC1RAB9ALMNAADORA3MAP3K5 | |
| SCHEMBL15363425 | 0.90 | LMNA (0.32) | NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL4968544 | 0.90 | LMNA (0.32) | NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL15975640 | 0.90 | LMNA (0.32) | NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL15363458 | 0.89 | NPC1 (0.35) | NPC1RAB9ALMNAADORA3MAP3K5 | |
| SCHEMBL10278858 | 0.88 | NPC1 (0.37) | NPC1RAB9ALMNAMAP3K5MAPK1 | |
| SCHEMBL15975675 | 0.87 | NPC1 (0.34) | NPC1RAB9ALMNAADORA3MAP3K5 | |
| SCHEMBL16269903 | 0.85 | NPC1 (0.36) | NPC1RAB9ALMNAADORA3MAP3K5 | |
| SCHEMBL14904691 | 0.85 | NPC1 (0.36) | NPC1RAB9ALMNAADORA3MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937083-B2 | Pesticidal compositions and processes related thereto | DowAgroSciences, LLC (US) | 2015-01-20 | — | — | US | disclosed |
| US-8937083-B2 | Pesticidal compositions and processes related thereto | DowAgroSciences, LLC (US) | 2015-01-20 | — | — | US | disclosed |
| US-8815271-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815271-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |