SCHEMBL15976228

SCHEMBL15976228

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nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
GABRR1 P24046 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16215968 0.83
SCHEMBL6851256 0.76
SCHEMBL7216876 0.76 KDM4E (0.37) KDM4ELMNAGABRR1
SCHEMBL22051412 0.74
SCHEMBL18103601 0.74 LTA4H (0.35)
SCHEMBL16454939 0.72 ANPEP (0.33)
SCHEMBL17347959 0.71 SLC7A5 (0.41)
SCHEMBL10140648 0.70
SCHEMBL20978336 0.70
SCHEMBL14306757 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996609-B1 METHOD OF PREPARING GLYCOPEPTIDES SCRIPPS RESEARCH INST (US) 2016-08-03 EP disclosed
US-20150343080-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS NOVO NORDISK AS (DK) 2015-12-03 US disclosed
US-8816050-B2 Method of preparing glycopeptides THE SCRIPPS RESEARCH INSTITUTE 2014-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150343080-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS PTMS, ANPEP, NGLY1 KDM4E 3684/4885LMNA 1603/4885GABRR1 1471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.