Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910274 | 1.00 | CTSL (0.32) | CTSLCTSSTDP1SMN1; SMN2 | |
| SCHEMBL15429738 | 1.00 | CTSL (0.32) | CTSLCTSSTDP1SMN1; SMN2 | |
| SCHEMBL8910571 | 1.00 | CTSL (0.32) | CTSLCTSSTDP1SMN1; SMN2 | |
| SCHEMBL12018320 | 1.00 | CTSL (0.32) | CTSLCTSSTDP1SMN1; SMN2 | |
| SCHEMBL18949041 | 1.00 | CTSL (0.32) | CTSLCTSSTDP1SMN1; SMN2 | |
| SCHEMBL825040 | 0.84 | CA12 (0.39) | CTSSSMN1; SMN2 | |
| SCHEMBL8907865 | 0.84 | CA12 (0.39) | CTSSSMN1; SMN2 | |
| SCHEMBL3266601 | 0.84 | CA12 (0.39) | CTSSSMN1; SMN2 | |
| SCHEMBL23277649 | 0.82 | CA14 (0.42) | CTSLCTSSSMN1; SMN2 | |
| SCHEMBL16255645 | 0.82 | SMN1; SMN2 (0.33) | CTSLCTSSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815928-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2014-08-26 | — | — | US | disclosed |