Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12020037 | 1.00 | MEN1 (0.34) | MEN1GAAMAPTRAB9AKMT2A | |
| SCHEMBL11957430 | 0.84 | — | — | |
| SCHEMBL2402362 | 0.83 | — | — | |
| SCHEMBL12334799 | 0.80 | — | — | |
| SCHEMBL12198546 | 0.80 | MAPT (0.44) | MEN1GAAMAPTKMT2A | |
| SCHEMBL15298854 | 0.80 | MAPT (0.44) | MEN1GAAMAPTKMT2A | |
| SCHEMBL6865311 | 0.79 | — | — | |
| SCHEMBL13078131 | 0.79 | — | — | |
| SCHEMBL12334225 | 0.79 | — | — | |
| SCHEMBL11957550 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815905-B2 | Propionic acids, propionic acid esters, and related compounds | PROMENTIS PHARMACEUTICALS, INC. (US) | 2014-08-26 | — | — | US | disclosed |