SCHEMBL12198546

SCHEMBL12198546

CSCCC1NC(=O)OC1=O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
HDAC8 Q9BY41 2/20 0.42
KMT2A Q03164 3/20 0.36
GAA P10253 1/20 0.36
CYP3A4 P08684 2/20 0.34
CYP2C19 P33261 1/20 0.34
CYP1A2 P05177 1/20 0.34
CACNA1G O43497 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 2/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15298854 1.00 MAPT (0.44) MAPTHDAC8KMT2AGAACYP3A4
SCHEMBL15976393 0.80 MEN1 (0.34) MAPTKMT2AGAAMEN1
SCHEMBL12020037 0.80 MEN1 (0.34) MAPTKMT2AGAAMEN1
SCHEMBL7662496 0.78 SMN1; SMN2 (0.34) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL7659302 0.74 ALDH1A1 (0.40) MAPTKMT2ACYP1A2KDM4EALDH1A1
SCHEMBL16117006 0.73
SCHEMBL11957430 0.73
SCHEMBL5283640 0.73 CYP1A2 (0.36) MAPTKMT2ACYP1A2KDM4EALDH1A1
SCHEMBL24608268 0.73 HDAC8 (0.53) MAPTHDAC8KMT2AGAACYP3A4
SCHEMBL762450 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024028255-A1 POLY(AMINO ACID) BASED CAPSULES AGFA-GEVAERT NV (BE) 2024-02-08 WO disclosed
WO-2022194759-A1 POLY(AMINO ACID) BASED CAPSULES AGFA-GEVAERT NV (BE) 2022-09-22 WO disclosed
US-20220144760-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND FUJIFILM CORPORATION (JP) 2022-05-12 US disclosed
US-20220135517-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND FUJIFILM CORPORATION (JP) 2022-05-05 US disclosed
WO-2021033505-A1 METHOD FOR PRODUCING CARBONYL COMPOUND AND FLOW REACTION SYSTEM USED FOR PRODUCTION OF CARBONYL COMPOUND 富士フイルム株式会社 2021-02-25 WO disclosed
WO-2021033504-A1 METHOD FOR PRODUCING CARBONYL COMPOUND AND FLOW REACTION SYSTEM USED FOR PRODUCTION OF CARBONYL COMPOUND 富士フイルム株式会社 2021-02-25 WO disclosed
EP-2035442-B1 NEW SUPPORTED OXIDATION REACTANTS, PROCESS FOR THEIR PREPARATION AND USES THEREOF CENTRE NAT RECH SCIENT (FR) 2011-10-12 EP disclosed
US-20110003943-A1 Supported Oxidation Reactants, Process for their Preparation and Uses Thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 2011-01-06 US disclosed
US-20110003943-A1 Supported Oxidation Reactants, Process for their Preparation and Uses Thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 2011-01-06 US disclosed
WO-2007144411-A1 NEW SUPPORTED OXIDATION REACTANTS, PROCESS FOR THEIR PREPARATION AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2007-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003943-A1 Supported Oxidation Reactants, Process for their Preparation and Uses Thereof DAO, MTR, MET MAPT 4100/4885HDAC8 4868/4885KMT2A 1336/4885
US-20220135517-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND PARG, PTGIS, MT-ATP8 MAPT 2131/4885HDAC8 4258/4885KMT2A 3614/4885
US-20220144760-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND NOXO1, MT-CO2, MT-ATP8 MAPT 2763/4885HDAC8 3359/4885KMT2A 2633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.